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Southern MO Ranch-400 Acres with Spring Creek in Thomasville, MO

2575 County Road 422, Thomasville, Missouri, 65438

* FOR SALE

$2,900,000

MLS: 24084-706600

400. Acres

2,496 SqFt

5 beds

2.0 baths

What You Should Know

  • Oregon County, Missouri Farm

  • So. Central Missouri Farm

  • Farm for Sale in Missouri

  • Missouri Ozarks Ranch for Sale

  • Ranch in Oregon County, MO

  • Missouri Hunting Land for Sale

  • Ranch w/Home & Timberland

  • Hunt, Fish & Farm the Ozarks

  • Central Air

  • Water Access

  • Outbuildings

  • Basement

Why You'll Love It

Southern Missouri Ranch – 400 Acres with Spring Creek in Thomasville, MO

Discover the perfect blend of productivity, privacy, and natural beauty with this exceptional Missouri Ozarks farm for sale in Oregon County. Spanning 400 acres, this ranch features a gorgeous year-round spring-fed creek, 200 acres of lush pasture and hayfields, and the balance in mature timberland. With five ponds, including a large spring-fed pond, this property is well-watered and ideal for cattle, horses, or a self-sufficient homestead.


Property Highlights

   400 acres – 200 acres open pasture/hay ground, balance in timber

   Year-round spring creek with abundant fish

   Five ponds, including a large spring-fed pond

   Fenced and cross-fenced with barbed wire for livestock

   Barn and equipment shed for storage and operations

   Three wells on the property

   Excellent hunting and fishing with abundant wildlife


The HomeA spacious 5 bedroom, 2 bath home with an unfinished basement offers room to expand. The residence boasts a beautiful new kitchen, open dining and living areas, plus a second kitchen for canning—perfect for homesteading. Covered front and back decks provide serene views of the ranch. Built with durable composite siding, the home is designed for low-maintenance living.


Lifestyle & LocationThis Southern Missouri ranch provides the ultimate setting for self-sufficient living, homesteading, or running livestock in a private, secluded environment. The rolling hills, fertile hayfields, and clear water sources make this a rare find.


Located in Thomasville, Missouri, you’ll enjoy being near some of the Ozarks’ most beautiful waterways, including the Eleven Point River, Jacks Fork River, and the Current River—all known for floating, fishing, and outdoor recreation. For big-city conveniences, West Plains, MO is just a short drive away, offering Ozarks Medical Center, Missouri State University-West Plains, shopping, dining, and cultural amenities.


Key Features:

   Oregon County ranch for sale – 400 acres with live water

   Pasture, hayfields, timber, and wildlife habitat

   Spacious 5BR/2BA home with unfinished basement

   Multiple water sources: spring creek, ponds, and wells

   Excellent hunting, fishing, and outdoor recreation

   Private setting yet convenient to West Plains

This property is a rare opportunity to own a large Missouri Ozarks farm and ranch with everything in place for livestock, recreation, or a sustainable lifestyle.

Where You'll Find It

  • Street Address: 2575 County Road 422
  • City: Thomasville
  • State: Missouri
  • County: Oregon

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Virtual Tour

Video Tour

Kimberly Grennan

Broker / Officer / Realtor®